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肝癌长期生存的现状研究(英文版) 读者对象:第一目标读者:肿瘤外科医师;第二目标读者:青年医师以及医学生
本书通过介绍复旦大学附属中山医院1961-1995年收治的、88例肝癌术后20~48年长期生存的实例,分析这88例肝癌长期生存概况,总结肝癌长期生存的八条经验及治疗途径,从而提出我国外科学者对肝癌本质的认识,非规则性肝切除是最主要的肝癌治疗模式,肝动脉手术与肝癌二步切除治疗是独具特色的肝癌治疗模式。本书以熟练的英文面向全球肝癌外科学者全面介绍了88例肝癌的治疗经过、成功经验、技术要点和作者对肝癌外科内涵的理解。其写作力求深入浅出、图文并茂,可供肿瘤外科医师、青年医师以及医学生参考阅读。
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Contents
Part I Eighty-Eight Illustrative Cases 1 Case 1 Recurrence 39 Years after Resection, Total Survival 43 Years 3 Case 2 A Single Resection, Ongoing Survival 48 Years 7 Case 3 Two Resections, Total Survival 44 Years 10 Case 4 A Single Resection, Total Survival 26 Years 12 Case 5 A Single Resection, Total Survival 34 Years 13 Case 6 A Single Resection of Giant Liver Cancer, Ongoing Survival 44 Years 14 Case 7 A Single Resection, Total Survival 20 Years 15 Case 8 Liver Resection and Resection of Pulmonary Metastasis, Total Survival 32 Years 16 Case 9 Two Resections, Ongoing Survival 40 Years 17 Case 10 Liver Resection and Resection of Pulmonary Metastasis, Total Survival 25 Years 18 Case 11 A Single Resection, Ongoing Survival 40 Years 19 Case 12 Oldest Survivor, Age 99, after Liver Resection and Subsequent Pulmonary Metastasis Resection, Ongoing Survival 40 Years 20 Case 13 A Single Resection, Ongoing Survival 40 Years 22 Case 14 A Single Resection, Total Survival 31 Years 23 Case 15 A Single Resection, Total Survival 34 Years 24 Case 16 A Single Resection, Ongoing Survival 36 Years 25 Case 17 A Single Resection, Total Survival 25 Years 26 Case 18 A Single Resection, Ongoing Survival 36 Years 27 Case 19 A Single Resection, Total Survival 29 Years 28 Case 20 A Single Resection, Ongoing Survival 35 Years 30 Case 21 A Single Resection, Ongoing Survival 35 Years 31 Case 22 Two-Step Resection and Resection of Recurrence, Ongoing Survival 35 Years 33 Case 23 A Single Resection, Ongoing Survival 34 Years 36 Case 24 Hepatic Artery Ligation and Cannulation with Infusion Hemotherapy, Ongoing Survival 32 Years 37 Case 25 A Single Resection, Total Survival 30 Years 38 Case 26 A Single Resection, Ongoing Survival 31 Years 39 Case 27 Two Resections, Ongoing Survival 31 Years 41 Case 28 Two Resections and Resection of Pulmonary Metastasis, Total Survival 20 Years 43 Case 29 A Single Resection, Ongoing Survival 31 Years 44 Case 30 A Single Resection, Total Survival 21 Years 45 Case 31 A Single Resection, Total Survival 26 Years 46 Case 32 Two-Step Resection, Total Survival 26 Years 47 Case 33 A Single Resection, Total Survival 28 Years 49 Case 34 A Single Resection, Ongoing Survival 30 Years 50 Case 35 Hepatic Artery Ligation and Cannulation with Infusion Chemotherapy, Total Survival 25 Years 51 Case 36 A Single Resection, Ongoing Survival 29 Years 52 Case 37 A Single Resection, Total Survival 20 Years 53 Case 38 Two-Step Resection, Ongoing Survival 29 Years 55 Case 39 A Single Resection, Ongoing Survival 29 Years 57 Case 40 A Single Resection, Ongoing Survival 29 Years 58 Case 41 Two Resections, Ongoing Survival 29 Years 59 Case 42 Two-Step Resection and Resection of Pulmonary Metastasis, Ongoing Survival 28 Years 60 Case 43 Two-Step Resection, Ongoing Survival 28 Years 64 Case 44 Two Resections, Total Survival 25 Years 65 Case 45 Two Resections, Ongoing Survival 28 Years 66 Case 46 Two Resections, Total Survival 27 Years 68 Case 47 Liver Resection and Hepatic Vein Cancer Thrombectomy, Ongoing Survival 28 Years 69 Case 48 Liver Resection and Bile Duct Cancer Thrombectomy, Total Survival 25 Years 71 Case 49 A Single Resection, Ongoing Survival 28 Years 72 Case 50 Liver Resection and Portal Vein Cancer Thrombectomy, Ongoing Survival 27 Years 73 Case 51 Two-Step Resection, Ongoing Survival 27 Years 75 Case 52 A Single Resection, Ongoing Survival 27 Years 77 Case 53 A Single Resection, Ongoing Survival 27 Years 78 Case 54 A Single Resection, Total Survival 26 Years 80 Case 55 Two-Step Resection, Ongoing Survival 26 Years 81 Case 56 A Single Liver Resection, Ongoing Survival 24 Years 82 Case 57 Two-Step Resection and Resection of Recurrence, Ongoing Survival 24 Years 83 Case 58 Resection of Bilateral Lesions, Ongoing Survival 23 Years 88 Case 59 Liver Resection and Hepatic Vein Cancer Thrombectomy, Ongoing Survival 23 Years 89 Case 60 A Single Resection, Ongoing Survival 23 Years 91 Case 61 A Single Resection, Ongoing Survival 23 Years 93 Case 62 A Single Resection, Ongoing Survival 23Years 94 Case 63 A Single Resection, Total Survival 22 Years 96 Case 64 A Single Resection, Ongoing Survival 22 Years 97 Case 65 Liver Resection for Metastases from Colon Cancer, Ongoing Survival 22 Years 99 Case 66 Resection of Hepatic Hilum Cancer, Ongoing Survival 22 Years 101 Case 67 A Single Resection, Ongoing Survival 22 Years 104 Case 68 A Single Resection, Ongoing Survival 22 Years 105 Case 69 A Single Resection in an 18 Months Child, Ongoing Survival 22 Years 106 Case 70 A Single Resection, Ongoing Survival 22 Years 108 Case 71 A Single Resection, Ongoing Survival 22 Years 109 Case 72 Liver Resection for Metastasis from Colon Cancer, Total Survival 21 Years 110 Case 73 A Single Resection, Ongoing Survival 21 Years 111 Case 74 A Single Resection, Ongoing Survival 21 Years 113 Case 75 Three Resections, Ongoing Survival 21 Years 114 Case 76 A Single Resection, Ongoing Survival 21 Years 117 Case 77 A Single Resection, Ongoing Survival 21 Years 118 Case 78 A Single Resection, Ongoing Survival 21 Years 119 Case 79 Two Resections, Ongoing Survival 21 Years 120 Case 80 A Single Resection, Ongoing Survival 20 Years 121 Case 81 Two Resections, Ongoing Survival 20 Years 122 Case 82 A Single Resection, Ongoing Survival 20 Years 124 Case 83 A Single Resection, Ongoing Survival 20 Years 125 Case 84 A Single Resection, Ongoing Survival 20 Years 126 Case 85 Two Resections, Ongoing Survival 20 Years 128 Case 86 A Single Resection, Ongoing Survival 20 Years 130 Case 87 A Single Resection, Ongoing Survival 20 Years 131 Case 88 Two-Step Resection of Liver Lymphoma, Ongoing Survival 20 Years 132 Part II Profile of 88 Cases with Long-Term Survival 135 Part III Gems to Take Home Experiences and Therapeutic Approaches 137 3.1 Hepatectomy is the Most Important Treatment for Liver Cancer. Long-Term Survival is Possible after a Single Liver Resection 139 3.2 Follow-Up Treatment with Resection of Recurrence Can Further Improve Therapeutic Efficacy 140 3.3 Long-Term Survival after 3 Successive Hepatectomies for Liver Cancer Further Strengthened the Value of Follow-up Treatment 142 3.4 Long-Term Survival after Liver Cancer Resection and Resection of Pulmonary Metastasis Again Highlighted the Value of Follow-up with Definitive Treatment 143 3.5 Long-Term Survival by Two-Step Liver Resection after Hepatic Artery Ligation with Cannulation and Intra-Arterial Infusion Chemotherapy to “Modify” the Cancer 145 3.6 Liver Resection with or Followed by Local Treatment for Liver Cancer is a New Approach to Prolong Survival 146 3.7 Long-Term Survival after Hepatectomy with Transcatheter Arterial Chemoembolization for Liver Cancer 148 References 152 Part IV Food for Thought on the Nature of Liver Cancer 155 4.1 Liver Cancer is a Systemic Disease as well as Local Disease. 156 4.2 Liver Cancer is a “Erocious Tiger” as well as a “Big Docile Cat” 157 4.3 Lung Metastasis Means the Disease is in a Late Stage, is not Entirely True 158 4.4 Do not Ignore the Value of Hepatic Artery Surgery in the Treatment of Liver Cancer 159 4.5 Multi-Modality Therapy is the Developing Trend, but Surgical Resection is Absolutely Irreplaceable in the Comprehensive Treatment 160 References 162 Part V Irregular Hepatectomy—the Mainstay Procedure in Liver Cancer Resection 163 5.1 Regular Hepatectomy 164 5.2 Irregular Hepatectomy 165 5.3 Application of Lip-Shaped Hepatectomy in Irregular Hepatectomy 166 5.4 Left Regular and Right Irregular Principle 171 5.5 Irregular Hepatectomy is Particularly Suitable for Liver Cancer at the Hepatic Hilum 171 5.6 Positive Evaluation of the Hepatic Hilum Occlusion Technique in Hepatectomy 173 5.7 The Concept of Radical Resection in Liver Cancer is Different from Other Solid Tumors 175 5.8 One Must Balance Outcome and Operative Risks 176 5.9 Suggestions to Reduce Mortality 177 References 180 Part VI Hepatic Artery Procedure and the Two-Step Resection for Liver Cancer 183 6.1 Mechanism of Hepatic Artery Procedure in the Treatment of Primary Liver Cancer 184 6.2 Hepatic Artery Ligation 185 6.3 Hepatic Artery Cannulation 187 6.4 Hepatic Artery Ligation with Cannulation 188 6.5 Operation in Detail 189 6.6 The Embedded Pump-Catheter Infusion System 191 6.7 Hepatic Intra-Arterial Chemotherapy via the Pump-Catheter System 193 6.8 Transcatheter Arterial Chemoembolization(TACE) 196 6.9 Two-Step Resection of Liver Cancer 197 6.10 Typical Cases in Hepatic Artery Therapy 198 References 210 Part VII Is Elevated Liver Enzymes in Liver Cancer a Surgical Contraindication? 213 References 218 Part VIII Challenges and Our Preliminary Efforts 219 References 229 Acknowledgement 231 Index 233
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