神经科学百科全书:细胞内转运与细胞骨架(英文版)(影印版)(导读版)
定 价:158 元
- 作者:斯奎尔 ,(Larry.R.Squire) 著
- 出版时间:2010/8/1
- ISBN:9787030280817
- 出 版 社:科学出版社
- 中图法分类:Q2
- 页码:674
- 纸张:胶版纸
- 版次:1
- 开本:16开
什么是百科全书?这一名词来自于两个希腊单词:enkuklios(意思是循环的)和paideia(意思是教育)。在16世纪早期,拉丁手稿的抄写者们将这两个单词合而为一,其在英语中演化为一个单词,意思是具有广泛指导意义的工具书(The American Heritage Dictionary,2000,Boston:Houghton Mifflin,p.589)。从其来源可见,其希腊文原词中蕴含着以探索、综合的方式努力获取知识的含义。无论是拉丁文还是英文,该单词泛指涵盖广泛领域知识的工具书。
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《神经科学百科全书:细胞内转运与细胞骨架(英文版)(影印版)(导读版)》书篇幅巨大,为所有神经科学百科全书之首。由来自世界各地的2400多位专家撰稿人合力打造,覆盖了神经科学全部主要领域。书中每个词条在收入书中之前均经过顾问委员会的同行评议,词条中均含有词汇表、引言、参考文献和丰富的交叉参考内容。 ·主编为著名神经科学家、美国神经科学学会前主席Larry R Squire。 ·内容平易.本科生即可读性。 ·深度和广度独一无二,足可满足专家学者的需要。 ·导读版精选啄书中的部分主题,按内容重新编排。更适合读者购买和阅读。
什么是百科全书?这一名词来自于两个希腊单词:enkuklios(意思是循环的)和paideia(意思是教育)。在16世纪早期,拉丁手稿的抄写者们将这两个单词合而为一,其在英语中演化为一个单词,意思是具有广泛指导意义的工具书(The American Heritage Dictionary,2000,Boston:Houghton Mifflin,p.589)。从其来源可见,其希腊文原词中蕴含着以探索、综合的方式努力获取知识的含义。无论是拉丁文还是英文,该单词泛指涵盖广泛领域知识的工具书。
希腊文中强调的以创造性手段获取知识,在神经科学领域尤其适用。神经科学本身就是一个非常新的名词。Francis Schmitt在本书第一版的前言中指出,本书的编写过程就是将不同领域的科学家们聚集在一起,冲击大脑研究中最顽固的难题。他推动建立了神经科学研究项目(Neuroscience Research Program,简称NRP)。早期的NRP成员包括一些学术巨匠,如因关于光合作用的研究获得诺贝尔奖的Melvin Calvin、诺贝尔奖获得者物理化学家Manfred Eigen、生物化学家Albert Lehninger,和当时正在努力破解基因编码的年轻分子生物学家Marshall Nirenberg。
细胞内信号级联与第二信使
Calcium-Calmodulin Kinase II (CaMKII) in Learning and Memory
Cyclic AMP (cAMP) Role in Learning and Memory
Eph Receptor Signaling and Spine Morphology
MAP Kinase Signaling in Learning and Memory
Neural Crest Cell Diversification and Specification: ErbB Role
Notch Pathway: Lateral Inhibition
Notch Signal Transduction: Molecular and Cellular Mechanisms
Retinoic Acid Signaling and Neural Patterning
Sonic Hedgehog and Neural Patterning
Synaptic Plasticity: Diacylglycerol Signalling Role
Wnt Pathway and Neural Patterning
细胞内转运与细胞骨架
Actin Cytoskeleton in Growth Cones, Nerve Terminals, and Dendritic Spines
AMPA Receptor Cell Biology/Trafficking
Axonal and Dendritic Identity and Structure: Control of
Axonal and Dendritic Transport by Dyneins and Kinesins in Neurons
Axonal mRNA Transport and Functions
Axonal Transport and ALS
Axonal Transport and Alzheimers Disease
Axonal Transport and Huntingtons Disease
Axonal Transport and Neurodegenerative Diseases
Axonal Transport Disorders
Axonal Transport Tracers
Cytoskeletal Interactions in the Neuron
Cytoskeleton in Plasticity
Dendrites: Localized Translation
Dendritic RNA Transport: Dynamic Spatio-Temporal Control of Neuronal Gene Expression
Dystrophin, Associated Proteins, and Muscular Dystrophy
Intermediate Filaments
LIM Kinase and Actin Regulation of Spines
Lysosome and Endosome Organization and Transport in Neurons
Microtubule Associated Proteins in Neurons
Microtubules: Organization and Function in Neurons
Mitochondrial Organization and Transport in Neurons
Myosin Transport and Neuronal Function
Neurofilaments: Organization and Function in Neurons
Neuronal Motility and Structure: MARK and GSK Pathways
NMDA Receptors, Cell Biology and Trafficking
Nuclear Movements in Neurons
Peroxisomes: Organization and Transport in Neurons
Prion Transport
Proteasome Role in Neurodegeneration
Protein Folding and the Role of Chaperone Proteins in Neurodegenerative Disease
Retrograde Neurotrophic Signaling
Slow Axonal Transport
Spectrin: Organization and Function in Neurons
Transport Dependent Damage Signaling
Vesicular Sorting to Axons and Dendrites
分泌与囊泡循环
Active Zone
Botulinum and Tetanus Toxins
Calcium Channel Subtypes Involved in Neurotransmitter Release
Calcium Channels and SNARE Proteins
CIRL/Latrophilins
Clathrin and Clathrin-Adaptors
Complexins
Cysteine-String Proteins (CSPs)
Dynamin
Endocytosis: Kiss and Run
Exocytosis: Ca2+-Sensitivity
Fusion Pore
Large Dense Core Vesicles (LDCVs)
Latrotoxin
Liprins, ELKS, and RIM-BP Proteins
Lysosomal System
Muncl3 and Associated Molecules
Muncl8
Neurexins
Neuroligins
Neurosecretion (Regulated Exocytosis in Neuroendocrine Cells)
Neurotransmitter Release from Astrocytes
Neurotransmitter Release: Synchronous and Asynchronous
NSF and SNAPs
Optical Monitoring of Exo- and Endocytosis
PHR (Pam/Highwire/RPM-l)
Piccolo and Bassoon
Presynaptic Receptor Signaling
Rab3
Rab3A Interacting Molecules (RIMs)
RNA Granules: Functions within Presynaptic Terminals and Postsynaptic Spines
SNAREs
Synapsins
Synaptic Plasticity: Short-Term Mechanisms
Synaptic Vesicle Protein-2 (SV2)
Synaptic Vesicles
Synaptojanin
Synaptotagmins
SynCAMs
Synucleins
Vesicle Pools
Vesicular Neurotransmitter Transporters
Voltage-Gated Calcium Channels
原书词条中英对照表
Though the E(spl) enhancerincludes high-affinity proneural binding sites, highlevels of proneural protein expression in the prospec-tive SOP cannot independently drive E(spl) geneexpression because in the absence of NotchIC, Su(H)functions as part of a repressor complex that ensuresgenes in the E(spl) complex are not expressed. Insurrounding non-SOP cells of the PNC, whereNotch is activated by the SOP cell, NotchIc makesSu(H) function as an activator to drive E(spl) geneexpression.The Complementary Role of Bearded Family Genesin the E(Spl) ComplexThe E(spl) complex also includes non-bHLH genes ofthe Bearded (Brd) family. Their expression is alsoregulated by Notch activation; however, unlike theE(spl) bHLH genes, they do not inhibit proneuralgene expression. Instead, they interfere with Deltafunction by inhibiting Neuralized mediated endocy-tosis of Delta, a step that is essential for effectiveactivation of Notch in the neighboring cell (Figure 2).toestablishment of a central biasing mechanism during